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Abuse and addiction are independent and distinctive from physical dependence and tolerance. Doctors should be mindful that habit will not be accompanied by concurrent tolerance and signs or symptoms of Bodily dependence in all addicts.Avoid ingesting grapefruit or consuming grapefruit juice although working with this medication unless your medical

Unusual conditions of agranulocytosis has Also been connected with acetaminophen use. In high doses, quite possibly the most severe adverse effect is a dose-dependent, perhaps lethal hepatic necrosis. Renal tubular necrosis and hypoglycemic coma also may happen.Instruct individuals to look for acetaminophen or APAP on offer labels rather than to im